Author

Beata Grygielska

University of BirminghamORCID 0000-0002-0018-9507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Dean Philip John KavanaghiD· 2 shared Julie RayesiD· 2 shared Juma El-AwaisiiD· 2 shared Aaron ScottiD· 1 shared Alexander G. BrilliD· 1 shared Alexandru ȘchiopuiD· 1 shared Aran SinganayagamiD· 1 shared Babu V NaiduiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Dean Philip John KavanaghORCID

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2 papers

Recent·Most cited

Neutrophil and NET-driven pulmonary microvascular injury following myocardial injury: attenuation by S100A8/A9 inhibition

Danielle R. Lezama, Orestis Katsoulis, Eloise Marriott, Beata Grygielska, Dean Philip John Kavanagh, Celine Hsi Chen, Millie M Jackson, Ellen Jenkins, Katie Spencer, Emmanuel Abimbola, Nawaal Kiwia, Rahul Y. Mahida, Davor Pavlović, Helen Michelle McGettrick, Babu V Naidu, , Juma El-Awaisi

This study shows that myocardial injury leads to pulmonary microvascular damage driven by neutrophils and S100A8/A9, which can be reduced by inhibiting S100A8/A9.

bioRxiv · Sep 12, 2025 · PreprintImmunology

Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice

Juma El-Awaisi, Gina Perrella, Nicolas Mayor, V. V. Tinkova, Simon J. Cleary, Beata Grygielska, Steve P. Watson, Jordan D. Dimitrov, Alexander G. Brill, Eman Hassan, Phillip L.R. Nicolson, Dean Philip John Kavanagh, Neena Kalia, Julie Rayes

This study shows that Syk inhibition reduces hemin-induced thromboinflammation and improves perfusion in the lungs and kidneys of sickle cell mice.

Arteriosclerosis Thrombosis and Vascular Biology · Aug 15, 2025Peer-reviewedPathology