Marius Ader

This study compares human iPSC-derived photoreceptors of different ages for transplantation into a mouse retinal degeneration model, showing structural integration and functional maturation.

This study shows that transplanted human photoreceptors integrate and mature better in mildly degenerated retinas than severely degenerated ones, depending on the retinal microenvironment.

The paper shows that passage 1 human iPSC-derived RPE cells form more extensive monolayers after transplantation compared to passage 2 cells, highlighting a subpopulation with higher transplantation potential.

This paper demonstrates that transplanted human photoreceptors from iPSC retinal organoids extensively incorporate into a murine cone degeneration model, leading to improved maturation, polarisation, and functional integration.

This study shows that transplanted pluripotent stem cell-derived cone precursors can restore light responses in mice with advanced retinal degeneration, despite low engraftment.