Author

Zhongyang Shen

Capital Medical UniversityORCID 0000-0001-9481-0407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Fanchong JianiD· 2 shared Lingling YuiD· 2 shared Ran AniD· 2 shared Ronghua JiniD· 2 shared Yuanling YuiD· 2 shared Yunlong CaoiD· 2 shared Ayijiang YisimayiiD· 1 shared Binmao ZhangiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

Fanchong JianORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Lack of ancestral SARS-CoV-2 imprinting promotes BA.3.2.2 infection in children

Xiao Niu, Dan Xiong, Peizhuo He, Lingling Yu, Y L Li, X L Cai, Ran An, Yao Wang, Rui Kong, Yuanling Yu, Jing Wang, Qianran Wang, Juan Huang, Binmao Zhang, Tianyuan Zhao, , Yunlong Cao

This study shows that the lack of ancestral SARS-CoV-2 immune imprinting in children makes them more susceptible to BA.3.2.2 infection, as it evades neutralizing antibodies typically present in adults.

Nature Microbiology · Oct 26, 2026Peer-reviewedImmunology

Omicron-specific naive B cell maturation alleviates immune imprinting induced by SARS-CoV-2 inactivated vaccine

Ayijiang Yisimayi, Weiliang Song, Jing Wang, Fanchong Jian, Yuanling Yu, Xiaosu Chen, Yanli Xu, Ran An, Yao Wang, Sun Haiyan, Peng Wang, Lingling Yu, Fei Shao, Ronghua Jin, Zhongyang Shen, , Yunlong Cao

The paper investigates how Omicron-specific naive B cell maturation after breakthrough infection alleviates immune imprinting from inactivated SARS-CoV-2 vaccines.

Emerging Microbes & Infections · Oct 3, 2024Peer-reviewedImmunology