Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses
Rituparna Chakrabarti, Lina María Jaime Tobón, Loujin Slitin, Magdalena Redondo Canales, Gerhard Hoch, Marina Slashcheva, Elisabeth Fritsch, Kai Bodensiek, Özge Demet Özçete, Mehmet Gültaş, Susann Michanski, Felipe Opazo, Jakob Neef, Tina Pangršič, Tobias Moser, Carolin Wichmann
This study uses optogenetics and electron tomography to analyze the ultrastructure of cochlear inner hair cell ribbon synapses during stimulation, showing increased docked synaptic vesicles and no evidence of homotypic fusion.
eLife · Dec 23, 2022Peer-reviewedNeuroscience