Author

Jakob Neef

Universitätsmedizin GöttingenORCID 0000-0002-4757-9385Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Assay:electronic health records· 1 Organism:rat· 1

Frequent Co-Authors

Tobias MoseriD· 4 shared Carolin WichmanniD· 2 shared Mehmet GültaşiD· 2 shared Susann MichanskiiD· 2 shared Anna M. SteyeriD· 1 shared Chad Paul GrabneriD· 1 shared Christian A. WurmiD· 1 shared Craig Curtis GarneriD· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersNeuroscience

Tobias MoserORCID

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4 papers

Recent·Most cited

Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses

Rituparna Chakrabarti, Lina María Jaime Tobón, Loujin Slitin, Magdalena Redondo Canales, Gerhard Hoch, Marina Slashcheva, Elisabeth Fritsch, Kai Bodensiek, Özge Demet Özçete, Mehmet Gültaş, Susann Michanski, Felipe Opazo, Jakob Neef, Tina Pangršič, Tobias Moser, Carolin Wichmann

This study uses optogenetics and electron tomography to analyze the ultrastructure of cochlear inner hair cell ribbon synapses during stimulation, showing increased docked synaptic vesicles and no evidence of homotypic fusion.

eLife · Dec 23, 2022Peer-reviewedNeuroscience

Piccolino regulates the architecture of the ribbon at cochlear inner hair cell synapses

Susann Michanski, Rohan Kapoor, Anna M. Steyer, Wiebke Möbius, Iris Früholz, Frauke Ackermann, Mehmet Gültaş, Craig Curtis Garner, F. Kent Hamra, Jakob Neef, Nicola Strenzke, Tobias Moser, Carolin Wichmann

This study investigates the role of piccolino in cochlear inner hair cell synapses, finding it contributes to active zone organization and is essential for normal synaptic transmission.

bioRxiv · Dec 15, 2022 · PreprintNeuroscience

Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy

Chad Paul Grabner, Isabelle Jansen, Jakob Neef, Tobias Weiß, Roman Schmidt, Dietmar Riedel, Christian A. Wurm, Tobias Moser

The paper uses MINFLUX nanoscopy to visualize the molecular architecture of the photoreceptor active zone, revealing a serially duplicated complex of bassoon-RIM2-ubMunc13-2-CAST.

bioRxiv · May 28, 2021 · PreprintNeuroscience

Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea

Yunfeng Hua, Xu Ding, Haoyu Wang, Fangfang Wang, Yan Lu, Jakob Neef, Yunge Gao, Tobias Moser, Hao Wu

The paper reconstructs neural circuitry in the mouse cochlea using electron microscopy, showing differences in efferent innervation of spiral ganglion neurons based on their synaptic connectivity with inner hair cells.

Cell Reports · Jan 1, 2021Peer-reviewedNeuroscience