Author

Tina Pangršič

Universitätsmedizin GöttingenORCID 0000-0002-7313-1648Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:electronic health records· 3 Research Focus:cell type annotation· 2

Frequent Co-Authors

Carolin WichmanniD· 2 shared David OestreicheriD· 2 shared Susann MichanskiiD· 2 shared Tobias MoseriD· 2 shared Aizhen Yang-Hood· 1 shared Andreas NeefiD· 1 shared Anna M. SteyeriD· 1 shared Antonio M. G. de DiegoiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Carolin WichmannORCID

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Author profile →

4 papers

Recent·Most cited

Persistence of vestibular function in the absence of glutamatergic transmission from hair cells

Mohona Mukhopadhyay, Ruchi Modgekar, Aizhen Yang-Hood, Kevin K. Ohlemiller, Valentin Militchin, Maolei Xiao, Zhijun Shen, Nicholas R. Rensing, Michael Wong, Suh Jin Lee, Rebecca P. Seal, Joseph C. Holt, Mark E. Warchol, Susan E. Maloney, Carla M. Yuede, , Tina Pangršič

This study shows that vestibular function remains normal in Vglut3-/- mice despite severe reduction in glutamatergic synaptic transmission, suggesting non-quantal transmission compensates for the loss.

Scientific Reports · Mar 23, 2026Peer-reviewedNeuroscience

CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells

David Oestreicher, Shashank Chepurwar, Kathrin Kusch, Vladan Rankovic, Sangyong Jung, Nicola Strenzke, Tina Pangršič

This study shows that CaBP1 and CaBP2 suppress CaV1.3 channel inactivation in inner hair cells, enabling sustained synaptic transmission and hearing.

eLife · Dec 24, 2024Peer-reviewedNeuroscience

Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses

Rituparna Chakrabarti, Lina María Jaime Tobón, Loujin Slitin, Magdalena Redondo Canales, Gerhard Hoch, Marina Slashcheva, Elisabeth Fritsch, Kai Bodensiek, Özge Demet Özçete, Mehmet Gültaş, Susann Michanski, Felipe Opazo, Jakob Neef, Tina Pangršič, Tobias Moser, Carolin Wichmann

This study uses optogenetics and electron tomography to analyze the ultrastructure of cochlear inner hair cell ribbon synapses during stimulation, showing increased docked synaptic vesicles and no evidence of homotypic fusion.

eLife · Dec 23, 2022Peer-reviewedNeuroscience

Macromolecular and electrical coupling between inner hair cells in the rodent cochlea

Philippe Jean, Tommi Anttonen, Susann Michanski, Antonio M. G. de Diego, Anna M. Steyer, Andreas Neef, David Oestreicher, Jana Kroll, Christos Nardis, Tina Pangršič, Wiebke Möbius, Jonathan Felix Ashmore, Carolin Wichmann, Tobias Moser

The paper shows that 30% of inner hair cells in the rodent cochlea form electrochemical mini-syncytia through membrane fusion, enhancing sound encoding sensitivity and reliability.

Nature Communications · Jun 25, 2020Peer-reviewedNeuroscience