MicrobiologybioRxivPreprint
Inhibition of systemic mammalian metabolism by carnitine mimics from the gut microbiota
Katja Thümmler, Shyam Basak, Heather Hulme…·Daniel M. Wall
This study investigates the systemic effects of microbiome-derived carnitine analogues in mice, showing carnitine depletion and mitochondrial dysfunction due to inhibition of carnitine biosynthesis.
DOI 10.1101/2025.11.11.687811