Daniel M. Wall

The paper identifies differentially expressed genes in specific brain regions of germ-free mice, highlighting microbiome influence on brain gene expression and potential relevance to neurological disease.

This study investigates the systemic effects of microbiome-derived carnitine analogues in mice, showing carnitine depletion and mitochondrial dysfunction due to inhibition of carnitine biosynthesis.

This study uses spatial biology to identify intestinal and systemic molecular drivers of inflammation in DSS-treated mice, revealing new insights into IBD-related systemic effects.

This study investigates how gut microbiome-derived metabolites affect intestinal barrier integrity and immune cell responses to infection at the cellular level.

This study characterizes prophages in Clostridium clostridioforme LM41, identifying 15 prophages and their potential roles in host fitness and genetic diversity.

The paper identifies novel therapeutic targets for AIEC infection by stratifying macrophages based on bacterial load and showing that targeting these pathways reduces AIEC replication.

The paper isolates and characterizes novel Clostridium XIVa strains from the murine gut, revealing genomic diversity driven by mobile genetic element acquisition and expanded biosynthetic potential.