John D. Tompkins

This study compares intrinsic cardiac neurons across humans, mice, and pigs, revealing species-specific differences in structure, function, and neuropeptide expression.

The paper identifies distinct subtypes of cardiac-innervating sympathetic neurons using viral tracing and single-cell RNA sequencing, revealing their unique physiological roles in stress responses.

The paper creates a comprehensive neuroanatomic atlas of the RAGP-SAN complex in porcine and human hearts, showing how intrinsic cardiac neurons control SAN automaticity and cardiac function.

The paper identifies peripheral neural circuits regulating heart rate in mice using optogenetic and viral vector strategies, revealing distinct roles of cholinergic and noradrenergic neurons.

This paper describes a protocol for producing and administering AAV-PHP vectors to label and manipulate cells in the mouse nervous system and organs, with guidelines for experimental design.