Keisuke Yonehara

The paper generates an Igfn1iCre knock-in mouse line to study type-7 bipolar cells during development and confirms Igfn1 expression in these cells and other retinal types.

The paper compares OKR phenotypes in Frmd7 and Chrnb2 mutant mice, finding distinct effects on horizontal and vertical OKR and spontaneous eye oscillations.

The paper improves a GABA sensor, iGABASnFR2, with higher sensitivity and faster kinetics, enabling better in vivo imaging of GABAergic transmission.

The paper uses a new GABA sensor to identify over 40 GABA-releasing neuron types in the mouse retina and shows how their spatial structure and release kinetics shape inhibitory signaling.

The paper investigates the dimensionality of neural responses in the mouse superior colliculus, finding globally high and locally low dimensionality, and proposes a multidimensional response model for classification.

This study demonstrates that self-complementary AAV1 with a strong promoter can enable recombinase-independent anterograde transsynaptic labeling in neural circuits.

The paper shows that the thalamic-basolateral amygdala pathway processes innate and learned threats differently, with distinct neural activity patterns and response mechanisms.

The paper measures glutamate input kinetics in retinal starburst amacrine cells and shows that proximal dendrites have higher vesicle release rates, supporting a space-time wiring model for direction selectivity.

The paper investigates how the visual cortex processes optic flow by analyzing monocular and binocular responses in mice, finding that binocular integration underlies optic flow representation in specific cortical areas.

The paper shows direction selectivity in retinal bipolar cell axon terminals, revealing that directionally-tuned glutamatergic inputs from bipolar cell boutons contribute to direction selectivity before DSGCs.

EyeLoop is an open-source eye-tracking system enabling dynamic experiments with low-cost hardware, supporting multiple species and closed-loop applications.

This study demonstrates that acetylcholine (ACh) signaling at retinal synapses exhibits both synaptic and non-synaptic transmission characteristics, with rapid currents and limited spread.

The paper shows VIP interneurons in the amygdala use adaptive disinhibitory gating to enable associative learning by distinguishing important from irrelevant information.