BioinformaticsACS Pharmacology & Translational SciencePeer-reviewed
Allosteric binders of ACE2 are promising anti-SARS-CoV-2 agents
Joshua E. Hochuli, Sankalp Jain, Cleber Camilo Melo-Filho…·Alexey V. Zakharov
The paper identifies five compounds that inhibit SARS-CoV-2 replication by binding to ACE2 without disrupting its enzymatic function, serving as potential acute treatments for COVID-19.
22 citations