Author

Aldrin Kay‐Yuen Yim

Washington University in St. LouisORCID 0000-0001-9562-2328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Jeffrey MilbrandtiD· 3 shared Robi David MitraiD· 2 shared A. Joseph BloomiD· 1 shared Aaron DiAntonioiD· 1 shared Amy M. StricklandiD· 1 shared Caitlin B. DingwalliD· 1 shared Colin L. KremitzkiiD· 1 shared Denis R. AveyiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersNeuroscience

Jeffrey MilbrandtORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 2, 2024

Biophysical Simulation Enables Multi-Scale Segmentation and Atlas Mapping for Top-Down Spatial Omics of the Nervous System

Lina Mohammed Ali, Aldrin Kay‐Yuen Yim, Emanuel Gerbi…·William Buchser

SiDoLa-NS uses synthetic images and multi-scale CNNs to achieve high-precision segmentation of nuclei and tissue structures in nervous system samples.

DOI 10.1101/2024.08.02.605366

mouserat

𝕏 PostBluesky

NeuroscienceJournal of Clinical InvestigationPeer-reviewedOct 26, 2022

Macrophage depletion blocks congenital SARM1-dependent neuropathy

Caitlin B. Dingwall, Amy M. Strickland, Sabrina W. Yum…·Jeffrey Milbrandt

This study shows that macrophage depletion reverses neuropathic symptoms in a mouse model of SARM1-dependent neuropathy caused by NMNAT2 variants.

40 citations

mouseexperimental assay

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NeurosciencebioRxivPreprintApr 24, 2018

Single cell RNAseq uncovers a robust transcriptional response to morphine by oligodendrocytes

Denis R. Avey, Sumithra Sankararaman, Aldrin Kay‐Yuen Yim…·Jeffrey Milbrandt

This study identifies morphine-induced gene expression changes in oligodendrocytes using single-cell RNA sequencing in mice, highlighting pathways related to myelination.

2 citations

mousescRNA-seq

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