Author

Prasanna Ekambaram

University of PittsburghORCID 0000-0001-9568-617XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Linda M. McAllister‐LucasiD· 2 shared Peter C. LucasiD· 2 shared Aivi T. NguyeniD· 1 shared Annie I. Arockiaraj· 1 shared Anushe Munir· 1 shared Ari M. MelnickiD· 1 shared Chaim T. SneidermaniD· 1 shared Dong HuiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Linda M. McAllister‐LucasORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedAug 10, 2026

MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression

J. Hofstatter Azambuja, Saigopalakrishna S. Yerneni, Lisa M. Maurer…·Linda M. McAllister‐Lucas

This study shows that inhibiting MALT1 protease in glioblastoma-associated macrophages reduces immunosuppression and tumor growth by reprogramming macrophages to an M1-like phenotype.

5 citations

mouseexperimental assay

𝕏 PostBluesky

GeneticsbioRxivPreprintMar 6, 2023

CRISPRa-induced upregulation of human LAMA1 compensates for LAMA2-deficiency in Merosin-deficient congenital muscular dystrophy

Annie I. Arockiaraj, Marie A. Johnson, Anushe Munir…·Dwi U. Kemaladewi

This study shows that CRISPRa-mediated upregulation of LAMA1 compensates for LAMA2 deficiency in MDC1A fibroblasts, reducing cell migration and related pathway activity.

4 citations

humanexperimental assay

𝕏 PostBluesky