Author

J. Hofstatter Azambuja

Mayo ClinicORCID 0000-0002-2416-7724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Aivi T. NguyeniD· 1 shared Ari M. MelnickiD· 1 shared Chaim T. SneidermaniD· 1 shared Dong HuiD· 1 shared Gabriela Nogueira DebomiD· 1 shared Gary KohanbashiD· 1 shared Hannah E. CrentsiliD· 1 shared Jeffrey A. Meridew· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aivi T. NguyenORCID

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1 paper

Recent·Most cited

MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression

J. Hofstatter Azambuja, Saigopalakrishna S. Yerneni, Lisa M. Maurer, Hannah E. Crentsil, Gabriela Nogueira Debom, Linda R. Klei, Mei Smyers, Chaim T. Sneiderman, Kristina Elsa Schwab, Rajesh Acharya, Aivi T. Nguyen, Josie L. Emery, John W. Little, Jeffrey A. Meridew, Yijen Lin Wu, , Linda M. McAllister‐Lucas

This study shows that inhibiting MALT1 protease in glioblastoma-associated macrophages reduces immunosuppression and tumor growth by reprogramming macrophages to an M1-like phenotype.

Nature Communications · Aug 10, 2026Peer-reviewedCancer Biology