Author

Marie A. Johnson

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Dwi U. KemaladewiiD· 3 shared Anushe Munir· 2 shared Annie I. Arockiaraj· 1 shared Ashley C. NwaforiD· 1 shared Dale W. Lewis· 1 shared Donna Beer StolziD· 1 shared Erik KoppesiD· 1 shared Hülya BayıriD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersImmunology

Dwi U. KemaladewiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Targeting Galectin-3 to modulate inflammation in LAMA2-deficient congenital muscular dystrophy

Yonne Karoline Tenório de Menezes, Jinseo Lee, Jia Qi Cheng-Zhang, Marie A. Johnson, Ruvindi N. Ranatunga, Dwi U. Kemaladewi

This study identifies Galectin-3 as a driver of inflammation in LAMA2-CMD and shows that inhibiting it reduces inflammation and fibrosis in a mouse model.

bioRxiv · Mar 12, 2025 · PreprintImmunology

Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a novel mouse model of Snyder-Robinson Syndrome

Oluwaseun Akinyele, Anushe Munir, Marie A. Johnson, Megan S. Perez, Yuan Gao, Jackson R. Foley, Ashley C. Nwafor, Yijen Lin Wu, Tracy Murray Stewart, Robert A. Casero, Hülya Bayır, Dwi U. Kemaladewi

This paper characterizes a mouse model of Snyder-Robinson Syndrome with a missense mutation in the Sms gene, revealing behavioral, neuroanatomical, and metabolic defects.

Disease Models & Mechanisms · Mar 11, 2024Peer-reviewedNeuroscience

Insulin secretion deficits in a Prader-Willi syndrome β-cell model are associated with a concerted downregulation of multiple endoplasmic reticulum chaperones

Erik Koppes, Marie A. Johnson, James J. Moresco, Patrizia Luppi, Dale W. Lewis, Donna Beer Stolz, Jolene K. Diedrich, John R. Yates, Ronald C. Wek, Simon C. Watkins, Susanne M. Gollin, Hyun Jung Park, Peter F. Drain, Robert D. Nicholls

This study identifies a reduction in ER chaperones in PWS β-cells, leading to impaired insulin secretion and ER stress.

PLoS Genetics · Apr 17, 2023Peer-reviewedGenetics

CRISPRa-induced upregulation of human LAMA1 compensates for LAMA2-deficiency in Merosin-deficient congenital muscular dystrophy

Annie I. Arockiaraj, Marie A. Johnson, Anushe Munir, Prasanna Ekambaram, Peter C. Lucas, Linda M. McAllister‐Lucas, Dwi U. Kemaladewi

This study shows that CRISPRa-mediated upregulation of LAMA1 compensates for LAMA2 deficiency in MDC1A fibroblasts, reducing cell migration and related pathway activity.

bioRxiv · Mar 6, 2023 · PreprintGenetics