Arnoud Sonnenberg

This study shows that transmembrane domain interactions in integrin β1-subunit are essential for proper folding and surface expression, with mutations disrupting these interactions causing functional impairments and embryonic lethality.

This study shows that integrin α3β1 is essential for alveolar-capillary barrier formation by regulating epithelial differentiation during lung development.

This study identifies Caskin2 as a novel talin-binding protein that enhances cell motility through interactions with Abi1 and the WAVE Regulatory Complex.