Author

EDUARDO C. SALIDO

Universidad de La LagunaORCID 0000-0001-9599-9854Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Angel Luis PeyiD· 3 shared Mario Cano‐MuñoziD· 3 shared Atanasio Gómez‐MulasiD· 2 shared Barbara CelliniiD· 1 shared Dmitry S. LoginoviD· 1 shared Francisco Conejero‐LaraiD· 1 shared Juan Luis Pacheco‐GarcíaiD· 1 shared Mirco DindoiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBiophysics

Angel Luis PeyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintApr 14, 2025

Phosphorylation of Ser81 in human AGT reversibly inactivate enzyme function and mimics catalytic defects of certain PH1-causing mutations

Sara Milosevic, Mario Cano‐Muñoz, EDUARDO C. SALIDO…·Angel Luis Pey

The paper shows phosphorylation of Ser81 in AGT inactivates the enzyme and mimics some PH1-causing mutations.

DOI 10.1101/2025.04.14.648764

humanproteomics

𝕏 PostBluesky

BiophysicsbioRxivPreprintApr 12, 2025

Nanobodies as therapies for loss-of-function misfolding diseases.

Atanasio Gómez‐Mulas, Mirco Dindo, Juan Luis Pacheco‐García…·Angel Luis Pey

This study develops and characterizes six nanobodies as potential therapeutics for PH1 by targeting misfolded AGT variants, showing high affinity and functional enhancement in cellular models.

DOI 10.1101/2025.04.12.648492

humanprotein structure

𝕏 PostBluesky

BiophysicsFEBS LettersPeer-reviewedNov 26, 2024

Thermodynamic versus kinetic basis for the high conformational stability of nanobodies for therapeutic applications

Atanasio Gómez‐Mulas, Mario Cano‐Muñoz, EDUARDO C. SALIDO, Angel Luis Pey

This study shows that nanobodies' thermal stability is primarily thermodynamic, using a two-state denaturation model across a wide temperature range.

14 citations

protein structurestatistical model

𝕏 PostBluesky