Aakanksha Jain

This paper constructs a human dorsal root ganglion reference atlas, identifying 22 neuronal subtypes and 10 non-neuronal cell types, and reveals functional differences between human and mouse DRG neurons.

This study demonstrates the use of lipid nanoparticles to deliver siRNA to dorsal root ganglion neurons, effectively silencing TRPV1 and reducing pain-related behaviors.

The paper builds harmonized cross-species cell atlases of DRG and TG, identifies 29 cell types across 6 species, and shows transcriptomic similarities and differences in sensory neurons.

This study shows that macrophages protect against sensory axon degeneration in diabetic neuropathy by delaying axonal loss through CCR2 signaling.

This study investigates how the secondary somatosensory cortex (S2) modulates mechanical and thermal sensitivity through distinct neural circuits compared to the primary somatosensory cortex (S1).

The paper constructs a database of receptor-ligand pairs and uses single-cell transcriptomics to identify injury-specific neuroimmune interactomes in inflammatory pain.