Author

Jason Karpac

Texas A&M UniversityORCID 0000-0001-9607-217XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

Conghui Li· 1 shared Mohamed MlihiD· 1 shared Xiangshuo Kong· 1 shared Xiaotong LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 2 mutual co-author links

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1 shared paperPhysiology

Conghui Li

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2 papers

Recent·Most cited

PhysiologyNucleic Acids ResearchPeer-reviewedJan 14, 2026

NF-κB restrains nutrient-dependent transcription programs through chromatin modulation in Drosophila

Xiangshuo Kong, Conghui Li, Jason Karpac

This study shows that NF-κB/Relish in Drosophila restricts nutrient-dependent metabolic transcription by modulating chromatin accessibility and histone acetylation.

1 citation

DrosophilaChIP-seq

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PhysiologybioRxivPreprintAug 28, 2025

Diacylglycerol metabolism drives host-pathogen responses during enteric infection in Drosophila

Xiaotong Li, Mohamed Mlih, Jason Karpac

This study shows that diacylglycerol (DAG) metabolism in Drosophila midgut enterocytes regulates host-pathogen responses by controlling defecation and bacterial clearance.

DOI 10.1101/2025.08.28.672769

Drosophilaexperimental assay

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