MicrobiologybioRxivPreprint
Lactate Oxidase (LctO) Acts as a Metabolic Checkpoint Restraining Streptococcus pneumoniae Invasion of Respiratory Epithelial Barriers
DOI 10.64898/2026.07.15.738724
Author
University of Mississippi Medical CenterORCID 0000-0001-9618-0197Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Anna Scasny, Babek Alibayov, Ngoc Hoang…·Jorge Eugenio Vidal
This study shows pneumococcus-derived H2O2 disrupts host TCA cycle and induces a Warburg-like metabolic shift in lung epithelial cells, enhancing bacterial survival.