MicrobiologybioRxivPreprint
Lactate Oxidase (LctO) Acts as a Metabolic Checkpoint Restraining Streptococcus pneumoniae Invasion of Respiratory Epithelial Barriers
DOI 10.64898/2026.07.15.738724
Author
Ana G. Jop Vidal
University of Mississippi Medical Center
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2024-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 23 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- ImmunologybioRxivPreprint
A pan-serotype human monoclonal antibody protects against pneumococcal infection by targeting multiple choline binding domain proteins
Anna L. McCormick, Behrouz Ghazi Esfahani, Caroline Katherine Page…·Jarrod J. Mousa
This paper identifies a human monoclonal antibody that protects against multiple pneumococcal serotypes by targeting conserved choline-binding domain proteins.
DOI 10.64898/2026.05.28.728567 - MicrobiologybioRxivPreprint
Metabolic Rewiring at the Pyruvate Node Drives Severe Pneumonia and T-Cell Suppression in Serotype 3 Streptococcus pneumoniae Infection
Kenichi Takeshita, Ana G. Jop Vidal, Jorge Eugenio Vidal
This study identifies a metabolic pathway in Streptococcus pneumoniae that drives pneumonia and immune evasion through oxygen-sensitive growth and membrane bleb formation.
DOI 10.64898/2026.02.13.705843 - MicrobiologybioRxivPreprint
Pneumococcal H2O2 Reshapes Mitochondrial Function and Reprograms Host Cell Metabolism
Anna Scasny, Babek Alibayov, Ngoc Hoang…·Jorge Eugenio Vidal
This study shows pneumococcus-derived H2O2 disrupts host TCA cycle and induces a Warburg-like metabolic shift in lung epithelial cells, enhancing bacterial survival.
DOI 10.1101/2025.05.22.655446 - MicrobiologyDrug Resistance UpdatesPeer-reviewed
Ultrastructural, metabolic and genetic determinants of the acquisition of macrolide resistance by Streptococcus pneumoniae
Xueqing Wu, Babek Alibayov, Xi Xiang…·Jorge Eugenio Vidal
This study identifies molecular and metabolic factors that influence the acquisition of macrolide resistance in Streptococcus pneumoniae through chromosomal and ICE integration.