MicrobiologybioRxivPreprint
Lactate Oxidase (LctO) Acts as a Metabolic Checkpoint Restraining Streptococcus pneumoniae Invasion of Respiratory Epithelial Barriers
DOI 10.64898/2026.07.15.738724
Author
University of Mississippi Medical CenterORCID 0009-0006-2085-6991Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Anna Scasny, Babek Alibayov, Ngoc Hoang…·Jorge Eugenio Vidal
This study shows pneumococcus-derived H2O2 disrupts host TCA cycle and induces a Warburg-like metabolic shift in lung epithelial cells, enhancing bacterial survival.
Xueqing Wu, Babek Alibayov, Xi Xiang…·Jorge Eugenio Vidal
This study identifies molecular and metabolic factors that influence the acquisition of macrolide resistance in Streptococcus pneumoniae through chromosomal and ICE integration.