Peter John Hunter

Genomic regulation of chemo-mechanical stability in plant-derived extracellular vesicles: a multiscale model of composite reinforcement

This paper develops a multiscale model to explain how plant genomic regulation enhances the mechanical stability of extracellular vesicles through composite reinforcement mechanisms.

A Computational Functional Tissue Unit of the Human Myometrium for In Silico Study of Gestational Excitability and Pathophysiology

The paper develops a multi-scale model of the human myometrium to study gestational excitability and pathophysiology, showing how tissue-level contractions emerge from single-cell electrophysiology and how inflammation can lead to preterm labour.

The biophysical basis of enterocyte homeostasis

The paper develops a bond graph model of enterocyte homeostasis, showing how physical laws constrain ion and glucose transport mechanisms to maintain cellular homeostasis.

High reelin expression can explain why the entorhinal cortex is a cradle for Alzheimer's disease

The paper shows that high reelin expression in alECLII neurons promotes A{beta}42 accumulation, leading to early neuronal demise in Alzheimer's disease.

Energy-based bond graph models of glucose transport with SLC transporters

The paper develops energy-based bond graph models of SLC transporters to conserve mass, charge, and energy, and demonstrates their application to glucose transport.

Mapping the Organization and Morphology of Calcitonin Gene-Related Peptide (CGRP)-IR Axons in the Whole Mouse Stomach

The paper maps the distribution and morphology of CGRP-IR axons in the whole mouse stomach using immunohistochemistry and 3D imaging techniques.

3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system

The paper creates a 3D single-cell anatomical map of the rat intrinsic cardiac nervous system, showing sex-dependent differences in neuron count and density while maintaining consistent spatial organization.

The SPARC DRC: Building a resource for the autonomic nervous system community

The paper describes the development of a resource for the autonomic nervous system community, including databases, connectivity maps, and simulation tools.

Model Annotation and Discovery with the Physiome Model Repository

The paper annotates biological models with semantic annotations and develops a web tool to help users discover relevant models in the Physiome Model Repository.