Jesús Jiménez‐Barbero

This study identifies CD11b as a noncanonical marker of cytotoxic competence in CD8+ T cells, enhancing their antitumor activity in mouse and human tumors.

This paper discovers non-carbohydrate inhibitors of Siglec-7:GD3 interactions using BiGEL libraries and validates their potency through SPR, ELISA, and NMR.

This study identifies CD24 as an innate immune checkpoint in colorectal cancer that promotes tumor survival by inhibiting macrophage-mediated clearance, validated through zebrafish models and human data.

This study shows that galectin-9 in dendritic cells is necessary for organizing HLA-II at immune synapses, which enhances CD4+ T cell activation and anti-tumor immunity.

This study identifies key residues in Siglec-10 involved in ligand recognition and shows that antibody blockade can restore CAR-T cell cytotoxicity.

This study shows that loss of UFMylation promotes prostate cancer metastasis by reprogramming glucose metabolism towards hexosamine biosynthesis.

This paper identifies 9-O-acetylated sialic acids as a ligand for the SARS-CoV-2 NTD, revealing a dual-receptor functionality in the S1 domain that was rapidly selected against.