Author

Stuart Fawke

University of CambridgeORCID 0000-0001-9669-1245Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2

Frequent Co-Authors

Janet Elwyn DeaneiD· 2 shared Stephen C. GrahamiD· 2 shared Alex S. NicholsoniD· 1 shared Benjamin G. ButtiD· 1 shared Chris H. HilliD· 1 shared Denisa KolářováiD· 1 shared Emily SmithiD· 1 shared Eve R. CaroeiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Janet Elwyn DeaneORCID

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2 papers

Recent·Most cited

Altered plasma membrane abundance of the sulfatide-binding protein NF155 links glycosphingolipid imbalances to demyelination

Shannon J. McKie, Alex S. Nicholson, Emily Smith, Stuart Fawke, Eve R. Caroe, James C. Williamson, Benjamin G. Butt, Denisa Kolářová, Ondřej Peterka, Michal Holčapek, Paul J. Lehner, Stephen C. Graham, Janet Elwyn Deane

The paper shows that altered sulfatide-binding by NF155 links glycosphingolipid imbalances to demyelination by affecting membrane protein abundance and axon-myelin contacts.

bioRxiv · Sep 15, 2022 · PreprintNeuroscience

The mechanism of sphingolipid processing revealed by a GALC-SapA complex structure

Chris H. Hill, Georgia M. Cook, Samantha J. Spratley, Stuart Fawke, Stephen C. Graham, Janet Elwyn Deane

The paper reveals the structure of the GALC-SapA complex, showing how it processes glycosphingolipids and explains saposin binding specificity.

Nature Communications · Jan 5, 2018Peer-reviewedMolecular Biology