Altered plasma membrane abundance of the sulfatide-binding protein NF155 links glycosphingolipid imbalances to demyelination
Shannon J. McKie, Alex S. Nicholson, Emily Smith, Stuart Fawke, Eve R. Caroe, James C. Williamson, Benjamin G. Butt, Denisa Kolářová, Ondřej Peterka, Michal Holčapek, Paul J. Lehner, Stephen C. Graham, Janet Elwyn Deane
The paper shows that altered sulfatide-binding by NF155 links glycosphingolipid imbalances to demyelination by affecting membrane protein abundance and axon-myelin contacts.
bioRxiv · Sep 15, 2022 · PreprintNeuroscience