Author

İlkin Yapici

Koç UniversityORCID 0000-0001-9686-4943Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Organism:human· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

Hasan DeMi̇rci̇iD· 2 shared A. Nazlı BaşakiD· 1 shared Arda Gorkem TokuriD· 1 shared Belgin SeveriD· 1 shared Bradley B. TolariD· 1 shared Cahine KulakmaniD· 1 shared Christopher A. FrancisiD· 1 shared Ebru DestaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Hasan DeMi̇rci̇ORCID

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2 papers

Recent·Most cited

Deciphering the altered conformational states of bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus

Ebru Destan, Jungmin Kang, Takehiko Tosha, Makina Yabashi, İlkin Yapici, Bradley B. Tolar, Cahine Kulakman, Zeliş Nergiz, Hiroaki Matsuura, Yoshiaki Kawano, Samuel Deutsch, Yasuo Yoshikuni, Christopher A. Francis, Soichi Wakatsuki A, Hasan DeMi̇rci̇

The paper determines ambient temperature structures of the bifunctional Nmar_1308 enzyme from Nitrosopumilus maritimus, revealing new conformational dynamics relevant to synthetic biology.

bioRxiv · Jul 7, 2025 · PreprintBiochemistry

Structural Insights into the Dynamics of Water in SOD1 Catalysis and Drug Interactions

İlkin Yapici, Arda Gorkem Tokur, Belgin Sever, Halil I. Ciftci, A. Nazlı Başak, Hasan DeMi̇rci̇

This study presents the crystal structure of human SOD1 and analyzes its structural dynamics and interactions with potential drug candidates for ALS treatment.

International Journal of Molecular Sciences · Apr 29, 2025Peer-reviewedMolecular Biology