Yoshiaki Kawano

This study investigates how water and anion coordination affect insulin's structure and stability across a pH range, revealing pH-dependent electrostatic effects on protein dynamics and stabilization.

The paper determines ambient temperature structures of the bifunctional Nmar_1308 enzyme from Nitrosopumilus maritimus, revealing new conformational dynamics relevant to synthetic biology.

This study presents near-physiological structures of the Fc fragment from a biosimilar VEGF-Trap and shows structural plasticity through molecular dynamics simulations.

This paper demonstrates the use of intensity-based hierarchical clustering to detect structural polymorphs in diffraction datasets from multiple crystals.