Author

Noemi D. Paguigan

University of UtahORCID 0000-0001-9686-7239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:rat· 1

Frequent Co-Authors

Albebson L. LimiD· 2 shared Baldomero M. OliveraiD· 2 shared Christopher A. ReillyiD· 2 shared Eric W. SchmidtiD· 2 shared Kevin ChaseiD· 2 shared Lee S. Leavitt· 2 shared Manju Karthikeyan· 2 shared Shrinivasan RaghuramaniD· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Albebson L. LimORCID

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2 papers

Recent·Most cited

The tunicate metabolite 2-(3,5-diiodo-4-methoxyphenyl)ethan-1-amine targets ion channels of vertebrate sensory neurons

Noemi D. Paguigan, Yannan Yan, Manju Karthikeyan, Kevin Chase, Jackson Carter, Lee S. Leavitt, Albebson L. Lim, Zhenjian Lin, Tosifa A. Memon, Sean B. Christensen, Bo Hjorth Bentzen, Nicole Schmitt, Christopher A. Reilly, Russell W. Teichert, Shrinivasan Raghuraman, , Eric W. Schmidt

This study identifies DIMTA, a marine tunicate metabolite, as a selective inhibitor of cold thermosensors in mice, increasing cold sensation threshold by >3°C.

ACS Chemical Biology · Aug 23, 2021Peer-reviewedNeuroscience

Nicotinic acetylcholine receptor partial antagonist polyamides from tunicates and their predatory sea slugs

Noemi D. Paguigan, Jortan O. Tun, Lee S. Leavitt, Zhenjian Lin, Kevin Chase, Cheryl D. Dowell, Cassandra E. Deering‐Rice, Albebson L. Lim, Manju Karthikeyan, Ronald W. Hughen, Jie Zhang, Randall Theodore Peterson, Christopher A. Reilly, Alan R. Light, Shrinivasan Raghuraman, , Eric W. Schmidt

The paper identifies molleamine C as a partial antagonist of nicotinic acetylcholine receptors with potential for neuroactive drug development.

ACS Chemical Neuroscience · Jul 2, 2021Peer-reviewedNeuroscience