Author

Yannan Yan

University of Copenhagen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:electronic health records· 1

Frequent Co-Authors

Bo Hjorth BentzeniD· 2 shared Albebson L. LimiD· 1 shared Audrey Thomson· 1 shared Baldomero M. OliveraiD· 1 shared Christopher A. ReillyiD· 1 shared Eric W. SchmidtiD· 1 shared Gary D. EwartiD· 1 shared Jackson CarteriD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Bo Hjorth BentzenORCID

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2 papers

Recent·Most cited

Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of k18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2

Gary D. Ewart, Michael D. Bobardt, Bo Hjorth Bentzen, Yannan Yan, Audrey Thomson, Klaus Klumpp, Stephen L. Becker, METTE MARIE ROSENKILDE, Michelle Miller, Philippe A. Gallay

This paper shows that BIT225, an E-protein inhibitor, reduces disease severity and increases survival in SARS-CoV-2 infected mice when administered before or after infection.

PLoS Pathogens · Aug 7, 2023Peer-reviewedMolecular Biology

The tunicate metabolite 2-(3,5-diiodo-4-methoxyphenyl)ethan-1-amine targets ion channels of vertebrate sensory neurons

Noemi D. Paguigan, Yannan Yan, Manju Karthikeyan, Kevin Chase, Jackson Carter, Lee S. Leavitt, Albebson L. Lim, Zhenjian Lin, Tosifa A. Memon, Sean B. Christensen, Bo Hjorth Bentzen, Nicole Schmitt, Christopher A. Reilly, Russell W. Teichert, Shrinivasan Raghuraman, , Eric W. Schmidt

This study identifies DIMTA, a marine tunicate metabolite, as a selective inhibitor of cold thermosensors in mice, increasing cold sensation threshold by >3°C.

ACS Chemical Biology · Aug 23, 2021Peer-reviewedNeuroscience