Author

Joel Benjamin Heim

Mayo ClinicORCID 0000-0001-9702-9480Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

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Adam NguyeniD· 1 shared Alexander MevesiD· 1 shared Benjamin J. MaddeniD· 1 shared Caleigh M. AzumayaiD· 1 shared Cristine Charlesworth· 1 shared Gabriele CordaraiD· 1 shared Hedda JohanneseniD· 1 shared Matthew C. ChaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Adam NguyenORCID

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1 paper

Recent·Most cited

BiochemistryStructurePeer-reviewedOct 1, 2026

Shared ligand-blocking mechanism but distinct conformational modulation by α5-targeting antibodies BIIG2 and MINT1526A

Adam Nguyen, Joel Benjamin Heim, Gabriele Cordara…·Melody G. Campbell

This study compares two anti-α5β1 antibodies, showing they share ligand-blocking mechanisms but differ in conformational modulation, with implications for therapeutic design.

DOI 10.1016/j.str.2026.08.001

humanexperimental assay

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