Author

Alexander Meves

Mayo ClinicORCID 0000-0001-7462-8288Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adam NguyeniD· 1 shared Benjamin J. MaddeniD· 1 shared Caleigh M. AzumayaiD· 1 shared Cristine Charlesworth· 1 shared Davis M. SeeligiD· 1 shared Debabrata MukhopadhyayiD· 1 shared Gabriele CordaraiD· 1 shared Hedda JohanneseniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Adam NguyenORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Shared ligand-blocking mechanism but distinct conformational modulation by α5-targeting antibodies BIIG2 and MINT1526A

Adam Nguyen, Joel Benjamin Heim, Gabriele Cordara, Matthew C. Chan, Hedda Johannesen, Cristine Charlesworth, Ming Li, Caleigh M. Azumaya, Benjamin J. Madden, Ute Krengel, Alexander Meves, Melody G. Campbell

This study compares two anti-α5β1 antibodies, showing they share ligand-blocking mechanisms but differ in conformational modulation, with implications for therapeutic design.

Structure · Oct 1, 2026Peer-reviewedBiochemistry

Vascular Endothelial Growth Factor as an Immediate-Early Activator of UV-induced Skin Injury

Stella P. Hartono, Victoria M. Bedell, Sk. Kayum Alam, Madelyn O’Gorman, MaKayla R. Serres, Stephanie R. Hall, Krishnendu Pal, Rachel A. Kudgus, Priyabrata Mukherjee, Davis M. Seelig, Alexander Meves, Debabrata Mukhopadhyay, Stephen Carl Ekker, Luke H. Hoeppner

This study shows that VEGF signaling is activated by UV exposure and that inhibiting it can prevent sunburn symptoms in mice, suggesting a new therapeutic approach for UV-induced skin damage.

bioRxiv · Jul 13, 2020 · PreprintMolecular Biology