Simon J. McGowan

CaptureCompendium provides software tools to simplify the design, analysis, and visualization of 3C experiments, addressing the need for specialized bioinformatics skills in genome folding studies.

The paper develops a platform combining ATAC-seq, DNaseI footprints, NG Capture-C, and machine learning to identify causal variants and genes for polygenic human traits.

This study introduces TARGET-seq, a method that simultaneously detects mutations and performs RNA-sequencing in single cells, revealing transcriptional and genetic tumor heterogeneity in myeloproliferative neoplasm cells.

CSynth is a 3D genome browser and chromatin structure modeller that enables real-time visualization and interaction with Hi-C data using GPU acceleration and VR.

This paper describes a valveless microfluidic device for isolating and sequencing single cancer cells, achieving high-quality genome coverage with minimal contamination.