Author

Sally‐Ann Clark

University of OxfordORCID 0000-0003-1720-7975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adam J. MeadiD· 2 shared Alba Rodríguez-MeiraiD· 2 shared Angela D. HambliniD· 2 shared Bethan PsailaiD· 2 shared Supat ThongjueaiD· 2 shared Alex J. CornishiD· 1 shared Alice GiustacchiniiD· 1 shared Amir EnshaeiiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Adam J. MeadORCID

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2 papers

Recent·Most cited

Cancer BiologyNature GeneticsPeer-reviewedJun 1, 2025

Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A

Charlotte K. Brierley, Bon Ham Yip, Giulia Orlando…·Adam J. Mead

The paper identifies chromothripsis-induced amplification of DYRK1A in blast phase MPN as a driver of aggressive disease and a potential therapeutic target.

14 citationstop 3%

humanbulk RNA-seq

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GenomicsMolecular CellPeer-reviewedFeb 11, 2019

Unraveling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA-sequencing

Alba Rodríguez-Meira, Gemma Buck, Sally‐Ann Clark…·Adam J. Mead

This study introduces TARGET-seq, a method that simultaneously detects mutations and performs RNA-sequencing in single cells, revealing transcriptional and genetic tumor heterogeneity in myeloproliferative neoplasm cells.

305 citationstop 1%

humanscRNA-seq

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