Molecular basis for the role of Ripr in Plasmodium falciparum invasion of human erythrocytes
Xiao Xiao, Qingmiao Zhou, Danushka S. Marapana, Thomas C. McLean, Rainbow W.B. Chan, Shabih Shakeel, Andrew P. Leis, Pailene S. Lim, Nicolai C Jung, Myo T. Naung, Sash Lopaticki, Matthew W. A. Dixon, Alyssa E. Barry, Alan F. Cowman, Stephen W. Scally
This study identifies EGF7 in PfRipr as a critical domain for inhibiting Plasmodium falciparum erythrocyte invasion and provides a basis for vaccine design.
bioRxiv · May 9, 2026 · PreprintBiochemistry