Adam Thomas

This study evaluates mRNA vaccines encoding PfMSP2, showing they induce strong IgG responses and functional antibodies against malaria merozoites, comparable to or better than a protein-based vaccine.

This study develops a self-amplifying RNA vaccine against Plasmodium falciparum malaria that induces high functional antibodies with Fc-mediated activities using a dose-sparing regimen.

This study identifies IgM as a key antibody isotype in immune responses against Plasmodium falciparum gametocytes, showing its superior complement fixation activity compared to IgG.