Werend Boesmans

Adrenergic signaling induces a pro-tumorigenic B cell state in colorectal cancer

This study shows adrenergic signaling promotes a pro-tumorigenic B cell state in colorectal cancer by altering their transcriptome and function, linking neuronal activity to immune responses and patient survival.

Luminal nutrients activate distinct patterns in submucosal and myenteric neurons in the mouse small intestine

The paper shows that different luminal nutrients activate distinct calcium responses in submucosal and myenteric neurons of the mouse small intestine.

D-Serine agonism of GluN1-GluN3 NMDA receptors regulates the activity of enteric neurons and coordinates gut motility

This study identifies D-serine and non-conventional GluN1-GluN3 NMDARs as regulators of enteric neuron activity and gut motility in mice and guinea-pigs.

Extracting neuronal activity signals from microscopy recordings of contractile tissue: a cell tracking approach using B-spline Explicit Active Surfaces (BEAS)

The paper introduces a cell tracking method using B-spline active contours to extract neuronal activity signals from moving contractile tissues, improving signal extraction in dynamic and overlapping cellular environments.

Nano-positioning and tubuline conformation determine transport of mitochondria along microtubules

The paper investigates how tubulin conformation and mitochondrial positioning affect anterograde transport along microtubules in vitro and in vivo.

Neuronal programming by microbiota enables environmental regulation of intestinal motility

The paper shows microbiota induce AhR in enteric neurons, enabling them to respond to environmental signals.