Pieter Vanden Berghe

This paper uses third-harmonic generation microscopy to visualize and measure mucociliary transport in human airway epithelium models without staining or processing.

This study characterizes mesenteric neurons in adult mice, showing they connect with the enteric nervous system and provide inhibitory feedback to the myenteric plexus during intestinal distension.

This study uses 4D-SLIDE microscopy to image the enteric nervous system in intact mouse intestines during contractions, resolving micrometer-scale movements without photodamage.

This study investigates spheroid fusion dynamics by measuring cell-cell tension and motility, revealing how tissue fluidity and visco-elastic properties influence fusion outcomes.

This study identifies PEX14 as a molecular link between optineurin and pexophagy, elucidating its role in recruiting autophagic machinery for peroxisome degradation.

The paper shows that different luminal nutrients activate distinct calcium responses in submucosal and myenteric neurons of the mouse small intestine.

The paper investigates the emergence of coordinated intestinal motility in human fetal development, identifying calcium dynamics and purinergic signaling as key drivers.

The paper shows that neuronal activity inhibits axonal mitochondrial transport in specific axonal regions during realistic firing patterns, but not in non-connecting segments.

This study identifies D-serine and non-conventional GluN1-GluN3 NMDARs as regulators of enteric neuron activity and gut motility in mice and guinea-pigs.

This study investigates neuronal activity in LRRK2-G2019S mutant neurons and finds increased spontaneous calcium transients and shorter inter-spike intervals.

The paper introduces a cell tracking method using B-spline active contours to extract neuronal activity signals from moving contractile tissues, improving signal extraction in dynamic and overlapping cellular environments.

This study shows that C9orf72 repeat expansions produce toxic arginine-rich DPRs that disrupt axonal transport by interacting with microtubules and motor proteins, contributing to ALS/FTD.

This study shows that TRPM3 upregulation in nociceptors contributes to heat hyperalgesia during inflammation, with pharmacological inhibition reducing TRPV1 and TRPA1 responses.

The paper investigates how tubulin conformation and mitochondrial positioning affect anterograde transport along microtubules in vitro and in vivo.

The paper shows microbiota induce AhR in enteric neurons, enabling them to respond to environmental signals.