Author
Max Delbrück CenterORCID 0000-0001-9852-677XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Tu Dang, Alexandra Roman, Anja Zimmer…·Ralf Kuehn
The paper introduces REPLACE, a CRISPR/Cas9-based method for homology-independent sequence replacement in non-dividing cells, achieving efficient gene and exon editing in primary cells and post-mitotic cardiomyocytes.
Paweł Lisowski, Selene Lickfett, Agnieszka Rybak‐Wolf…·Alessandro Prigione
This study shows that mutant Huntingtin causes neurodevelopmental issues in human brain organoids by disrupting CHCHD2, leading to mitochondrial and metabolic problems.
Sílvia Carvalho, Luna Zea-Redondo, Tsz Ching Chloe Tang…·Ana Pombo
This study shows that SRRM2 splicing factor dosage affects embryonic stem cell pluripotency and lineage commitment, with implications for developmental diseases and tumorigenesis.