Vimentin promotes collective cell migration through collagen networks via increased matrix remodeling and spheroid fluidity
Minh Tri Ho Thanh, Arun Poudel, Shabeeb Ameen…·Alison E. Patteson
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Syracuse UniversityORCID 0000-0002-4004-1734Unclaimed ORCID profile · follow to get notified of new preprints
11 papers
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Minh Tri Ho Thanh, Arun Poudel, Shabeeb Ameen…·Alison E. Patteson
Maxx Swoger, Minh Tri Ho Thanh, Renita Saldanha…·Alison E. Patteson
This study shows vimentin enhances nuclear deformation in polarized cells by linking to nesprin-3 and transmitting forces through the nuclear envelope.
Tao Zhang, Shabeeb Ameen, Sounok Ghosh…·J. M. Schwarz
This study uses a computational model to show that fluid-like tumor spheroids cause more ECM remodeling than solid-like spheroids due to shape fluctuations and cellular motility.
Ana Nicolle Strat, Suhani Patel, Minh‐Tri Ho Thanh…·Preethi S. Ganapathy
This study investigates how compressive strain affects astrocyte morphology, metabolism, and ECM modification in a 3D hydrogel model of the optic nerve head.
Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski…·Robert Bucki
This study shows extracellular vimentin and its citrullinated form activate TLR4 on human neutrophils, influencing migration, NET formation, and pathogen phagocytosis differently.
Fitzroy J. Byfield, Behnaz Sadat Eftekhari, Kaeli Kaymak-Loveless…·Paul A. Janmey
This study shows that BRG1 activity fluidizes the nucleus, altering its stiffness and dissipating mechanical energy, with implications for nuclear mechanics and remodeling.
Nuzhat Faiza, Roy D. Welch, Alison E. Patteson
This study shows that substrate stiffness affects the collective expansion of Myxococcus xanthus colonies, with adventurous motility playing a key role in sensing and responding to surface stiffness.
Julie Pinchiaroli, Renita Saldanha, Alison E. Patteson…·Bekele Gurmessa
This study investigates the mechanical properties of actin-vimentin composites using optical tweezers microrheology, revealing scale-dependent interactions that influence stress response and rheological behavior.
Jessica A. Comstock, Merrill E. Asp, Fatmagül Bahar…·Roy D. Welch
The paper uses phenotypic similarity to assess functional redundancy in homologous gene families of Myxococcus xanthus, showing mutant strains cluster by gene family.
Alison E Patteson, Junyi Yang, Paulo E Arratia, Arvind Gopinath
This study examines how light exposure affects collective motility in swarming Serratia marcescens colonies, identifying conditions under which mobility is suppressed or reversed.