Author

Manuel Lessi

University of MilanORCID 0000-0001-9898-7605Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alessia Valenti· 2 shared Carlo Emanuele VillaiD· 2 shared Cristina CheroniiD· 2 shared Davide BulgheresiiD· 2 shared Davide CastaldiiD· 2 shared Giuseppe TestaiD· 2 shared Marco Tullio RigoliiD· 2 shared Nicolò CaporaleiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Alessia Valenti

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 14, 2025

A molecular cell atlas of endocrine signalling in human neural organoids

Gaja Matassa, Marco Tullio Rigoli, Davide Castaldi…·Giuseppe Testa

This paper creates a molecular atlas of endocrine signaling in human neural organoids by perturbing seven hormonal pathways and analyzing their effects on neurodevelopment.

2 citations

humanbulk RNA-seq

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NeuroscienceNature MethodsPeer-reviewedDec 9, 2024

Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single cell resolution

Nicolò Caporale, Davide Castaldi, Marco Tullio Rigoli…·Giuseppe Testa

The paper develops and validates multiplexing strategies for brain organoids combined with single cell RNA-seq to study neurodevelopmental trajectories across multiple genetic lines.

35 citationstop 3%

humanscRNA-seq

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