Author

Alessia Valenti

University of Milan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Cristina CheroniiD· 3 shared Giuseppe TestaiD· 3 shared Marco Tullio RigoliiD· 3 shared Nicolò CaporaleiD· 3 shared Sarah StucchiiD· 3 shared Alessandro VitrioloiD· 2 shared Benedetta MudaiD· 2 shared Carlo Emanuele VillaiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersDevelopmental Biology

Cristina CheroniORCID

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3 papers

Recent·Most cited

High resolution multi-scale profiling of embryonic germ cell-like cells derivation reveals pluripotent state transitions in humans

Sarah Stucchi, Lessly P. Sepulveda-Rincon, Camille Dion, Gaja Matassa, Alessia Valenti, Cristina Cheroni, Alessandro Vitriolo, Filippo Prazzoli, George Young, Marco Tullio Rigoli, Riccardo Nagni, Martina Ciprietti, Benedetta Muda, Zoe Heckhausen, Petra Hájková, , Harry G. Leitch

This paper establishes a defined feeder-free system to convert human PGC-like cells to pluripotent stem cells, tracking transcriptional and epigenomic transitions using multi-omic analysis.

Stem Cell Reports · Dec 19, 2025Peer-reviewedDevelopmental Biology

A molecular cell atlas of endocrine signalling in human neural organoids

Gaja Matassa, Marco Tullio Rigoli, Davide Castaldi, Alessia Valenti, Manuel Lessi, Nicolò Caporale, Sarah Stucchi, Benedetta Muda, Riccardo Nagni, Luca Tommaso Mainardi, Alessandro Melon, Amaia Tintori, Davide Bulgheresi, Michal Kubacki, Sebastiano Trattaro, , Giuseppe Testa

This paper creates a molecular atlas of endocrine signaling in human neural organoids by perturbing seven hormonal pathways and analyzing their effects on neurodevelopment.

bioRxiv · Aug 14, 2025 · PreprintMolecular Biology

Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single cell resolution

Nicolò Caporale, Davide Castaldi, Marco Tullio Rigoli, Cristina Cheroni, Alessia Valenti, Sarah Stucchi, Manuel Lessi, Davide Bulgheresi, Sebastiano Trattaro, Martina Pezzali, Alessandro Vitriolo, Alejandro Tobon, Matteo Bonfanti, Dario Ricca, Katharina Schmid, , Giuseppe Testa

The paper develops and validates multiplexing strategies for brain organoids combined with single cell RNA-seq to study neurodevelopmental trajectories across multiple genetic lines.

Nature Methods · Dec 9, 2024Peer-reviewedNeuroscience