NeurosciencebioRxivPreprint
ZDHHC17 Links S-Acylation, Huntington Disease, VCP-associated Multisystem Proteinopathy, and Amyotrophic Lateral Sclerosis.
Firyal Ramzan, Gyana Gourab Mishra, Yasmeen Alshehabi…·Dale D. O. Martin
This study identifies ZDHHC17 as a key enzyme linking S-acylation to neurodegenerative diseases by modulating protein localization and toxicity.