Author

Gamma Chi

University of OxfordORCID 0000-0001-9910-0965Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:protein structure prediction· 3 Assay:protein structure· 2 Assay:bulk RNA-seq· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

David Bryant SaueriD· 3 shared Ashley C. W. PikeiD· 2 shared Abigail P JarretiD· 1 shared Alex N. BullockiD· 1 shared Álvaro Inglés‐PrietoiD· 1 shared András HerneriD· 1 shared András KotschyiD· 1 shared Anna LiiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBiochemistry

David Bryant SauerORCID

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintNov 3, 2026

Structural Basis for Inhibition of Human Anion Transporter SLC26A6/PAT-1

Gamma Chi, Tina Bohstedt, Roslin Adamson…·David B. Sauer

This study reports cryo-EM structures of human PAT-1 with inhibitors to elucidate their inhibition mechanisms and domain interactions.

DOI 10.64898/2026.11.01.757131

𝕏 PostBluesky

Systems BiologyMolecular Systems BiologyPeer-reviewedMay 12, 2025

Metabolic mapping of the human solute carrier superfamily

Tabea Wiedmer, Shao Thing Teoh, Eirini Christodoulaki…·Giulio Superti‐Furga

The paper systematically evaluates the metabolic and transcriptional effects of SLC superfamily members, identifying new substrates and functional groups.

20 citationstop 2%

humanmetabolomics

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Molecular BiologyNature CommunicationsPeer-reviewedApr 2, 2025

Structural mimicry of UM171 and neomorphic cancer mutants co-opts E3 ligase KBTBD4 for HDAC1/2 recruitment

Zhuoyao Chen, Gamma Chi, Timea Baló…·Alex N. Bullock

The paper identifies how neomorphic KBTBD4 mutations and the drug UM171 recruit HDAC1/2 complexes through structural mimicry, revealing a common mechanism for their degradation.

10 citations

humanprotein structure

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NeurosciencebioRxivPreprintDec 13, 2024

Structures of the human adult muscle-type nicotinic receptor in resting and desensitised states

Anna Li, Ashley C. W. Pike, Richard G. Webster…·Yin Yao Dong

The paper presents structures of human adult muscle-type nicotinic receptors in resting and desensitised states and examines the effects of genetic variants on channel function.

DOI 10.1101/2024.12.13.624530

humanprotein structure

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