V Reinke

Identification of germline chromatin modifying factors that influence zygotic transcription activation in C. elegans

The paper identifies chromatin regulatory factors in C. elegans germline that influence zygotic transcription activation during oocyte-to-embryo transition.

Binding profiles for 954 Drosophila and C. elegans transcription factors revealtissue specific regulatory relationships

The paper presents a catalog of transcription factor binding sites in Drosophila and C. elegans, revealing tissue-specific regulatory relationships using machine learning.

Distribution and dynamics of chromatin states in the C. elegans germ line

The paper defines chromatin states in C. elegans germ nuclei using histone modification and chromatin accessibility data, showing dynamic changes during germ cell differentiation.

The Upstream Sequence Transcription Complex Dictates Nucleosome Positioning and Promoter Accessibility at piRNA Genes in the C. elegans Germ Line

The paper shows that the USTC complex influences nucleosome positioning and promoter accessibility at piRNA genes in C. elegans germ line clusters.

To mock or not: a comprehensive comparison of mock IP and DNA input for ChIP-seq

This study compares mock IP and DNA input controls in ChIP-seq, showing that mock IP better removes spurious sites, while DNA input has unique advantages, and proposes combining both for improved binding site detection.

A simple and effective method to isolate germ nuclei from C. elegans for genomic assays.

This paper introduces a method to isolate high-purity germ nuclei from C. elegans for genomic analyses like ChIP-seq and RNA-seq, without requiring specialized strains or conditions.