Cell BiologybioRxivPreprint
A druggable ATP13A3-antizyme switch controls adaptive polyamine uptake in cancer
Alain René Schoofs, Jialin Chen, Rania Abou El Asrar…·Peter Vangheluwe
This study identifies ATP13A3-antizyme regulation as a mechanism for adaptive polyamine uptake in cancer, showing that targeting ATP13A3 with AMXT 1501 can block this response.
DOI 10.64898/2026.07.01.735759