Author

Alain René Schoofs

KU LeuvenORCID 0009-0007-1690-6324Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1

Frequent Co-Authors

Chris Van den HauteiD· 2 shared Mujahid AzfariD· 2 shared Peter VangheluweiD· 2 shared Steven H. L. VerhelstiD· 2 shared Youri FaytiD· 2 shared Angelika Bongers· 1 shared Anna VercautereniD· 1 shared Arti Sukhai· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Chris Van den HauteORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 1, 2026

A druggable ATP13A3-antizyme switch controls adaptive polyamine uptake in cancer

Alain René Schoofs, Jialin Chen, Rania Abou El Asrar…·Peter Vangheluwe

This study identifies ATP13A3-antizyme regulation as a mechanism for adaptive polyamine uptake in cancer, showing that targeting ATP13A3 with AMXT 1501 can block this response.

DOI 10.64898/2026.07.01.735759

humanproteomics

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Cancer BiologyMolecular OncologyPeer-reviewedFeb 21, 2025

The polyamine transporter ATP13A3 mediates DFMO-induced polyamine uptake in neuroblastoma

Mujahid Azfar, Weiman Gao, Chris Van den Haute…·Klaartje Somers

This study identifies ATP13A3 as a polyamine transporter mediating DFMO-induced polyamine uptake in neuroblastoma, highlighting it as a therapeutic target.

18 citationstop 5%

humanproteomics

𝕏 PostBluesky