Author

Claire A. Mitchell

Cancer Research UK Scotland InstituteORCID 0000-0001-9960-2340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Colin NixoniD· 2 shared Karen BlythiD· 2 shared Adiba KhaniD· 1 shared Alessandra I. RiggioiD· 1 shared Alex L. Young· 1 shared America V. CamposiD· 1 shared Amy LawloriD· 1 shared Cassie J. ClarkeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Colin NixonORCID

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2 papers

Recent·Most cited

Cancer BiologyBritish Journal of CancerPeer-reviewedMay 7, 2026

Runx1 and Runx2 act in concert to suppress Wnt/β-catenin-driven mammary tumourigenesis

Alessandra I. Riggio, Kerri Sweeney, Robin Shaw…·Karen Blyth

This study shows that Runx1 and Runx2 suppress Wnt/β-catenin-driven mammary tumourigenesis, with combined loss leading to increased tumour development and oncogenic pathway activation.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyThe Journal of Cell BiologyPeer-reviewedMay 7, 2025

Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments

Michalis Gounis, America V. Campos, Engy Shokry…·Cassie J. Clarke

The paper shows that breast cancer micrometastases alter metabolism to change extracellular vesicle production, creating an invasive microenvironment.

6 citations

mouseproteomics

𝕏 PostBluesky