Author

Chou‐Long Huang

University of IowaORCID 0000-0001-9963-3040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biophysics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adrian RothenfluhiD· 1 shared Aylin R. RodaniD· 1 shared Biswajit PadhyiD· 1 shared Chih‐Jen ChengiD· 1 shared Danish IdreesiD· 1 shared Gaëlle Mercenne· 1 shared Iris TitosiD· 1 shared Jeffrey N. SchellingeriD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Adrian RothenfluhORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 31, 2025

Endoplasmic reticulum-mitochondrion disconnection promotesmetabolic reprogramming and cystogenesis in polycystic kidneydisease

Biswajit Padhy, Jian Xie, Danish Idrees…·Chou‐Long Huang

This study shows that ER-mitochondria disconnection in ADPKD causes metabolic reprogramming and cyst formation, and restoring this connection reduces disease symptoms.

DOI 10.1101/2025.10.31.685870

mouseexperimental assay

𝕏 PostBluesky

BiophysicsScientific ReportsPeer-reviewedJan 2, 2025

Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy

Nicholas Schnicker, Zhen Xu, Mohammad Amir…·Chou‐Long Huang

This study reveals the conformational landscape of soluble α-klotho using cryo-EM, showing flexibility and multiple forms that support its FGFR-independent functions.

5 citations

cryo-EMexperimental assay

𝕏 PostBluesky

NeuroscienceCurrent BiologyPeer-reviewedMar 1, 2022

Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade

Jeffrey N. Schellinger, Qifei Sun, John M. Pleinis…·Aylin R. Rodan

The paper shows that chloride levels in Drosophila pacemaker neurons regulate circadian rhythms via a WNK-Fray signaling cascade and potassium channel activity.

18 citations

Drosophilaelectronic health records

𝕏 PostBluesky