Author

Xiao‐Man Liu

Broad InstituteORCID 0000-0001-9968-3988Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

Bryan J. SongiD· 3 shared Hasmik KeshishianiD· 3 shared Kira A. Perzel MandelliD· 3 shared Morgan ShengiD· 3 shared Steven A. CarriD· 3 shared Amy DeikiD· 2 shared Antia Valle-TojeiroiD· 2 shared Chuhan GengiD· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Bryan J. SongORCID

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3 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedNov 28, 2025

Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder

Bryan J. Song, Yang Ge, Ally A. Nicolella…·Morgan Sheng

This study investigates Akap11 mutant mice to explore the neurobiological effects of AKAP11 loss, finding increased PKA activity and transcriptomic changes linked to schizophrenia and bipolar disorder.

17 citationstop 1%

mousebulk RNA-seq

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Cell BiologybioRxivPreprintApr 25, 2025

Abnormal Lipid Metabolism and Altered Neuronal Support by Astrocytes Lacking Akap11, a Risk Gene for Schizophrenia and Bipolar Disorder

Xiao‐Man Liu, Horia Pribiag, Deeksha Misri…·Morgan Sheng

This study identifies AKAP11's role in regulating lipid metabolism and neuronal support in astrocytes, linking its dysfunction to schizophrenia and bipolar disorder risk.

6 citations

mouseproteomics

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NeurosciencebioRxivPreprintFeb 18, 2025

Epigenetic changes, neuronal dysregulation and metabolomic abnormalities in Zmym2 mutant mice, a genetic model of schizophrenia and neurodevelopmental disorders

Wei-Chao Huang, Kira A. Perzel Mandell, Sameer Aryal…·Morgan Sheng

2 citations

mousebulk RNA-seq

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